Acute Lymphoblastic Leukaemia Presenting as Aplastic Anaemia
نویسندگان
چکیده
منابع مشابه
Aplastic anaemia, acute myeloblastic leukaemia, and oxymetholone.
Four patients developed acute myeloblastic leukaemia after treatment of aplastic anaemia with oxymetholone. Two had previously shown an excellent clinical response to the drug and a third some improvement. Though no definite causal relationship between therapy and the onset of leukaemia has been established, the number of cases is greater than might have been expected by chance. The association...
متن کاملDistinction between aleukaemic prodrome of childhood acute lymphoblastic leukaemia and aplastic anaemia.
AIMS To document the features of the so-called aplastic presentation of childhood acute lymphoblastic leukaemia (ALL) and to determine whether this prodrome can be distinguished from aplasia. METHODS The peripheral blood and bone marrow appearances of all cases of childhood ALL presenting in one health region of England in 13 years and eight months were reviewed. All cases presenting with cyt...
متن کاملArthritis as presenting manifestation of acute lymphoblastic leukaemia in children.
BACKGROUND At disease onset, children with acute lymphoblastic leukaemia (ALL) may present with arthralgia or even signs of arthritis. This might cause misdiagnosis and thereby lead to prolonged diagnostic delay. The present study aimed to identify children with ALL with joint involvement and to compare their characteristics and outcome with children with ALL without joint involvement. METHOD...
متن کاملHypercalcaemia: an unusual presenting feature of childhood acute lymphoblastic leukaemia.
A 3-year-old boy was referred for management of severe symptomatic hypercalcaemia. His parents reported increasing lower limb pain and weakness over the preceding 4 months. Examination indicated a bedbound, pale, irritable child with generalized bony tenderness and peripheral lymphadenopathy; there were no palpable abdominal masses. The serum calcium was 5 3 mmol/l; serum phosphate, alkaline ph...
متن کاملAcute Lymphoblastic Leukaemia
Acute lymphoblastic leukaemia (ALL) is a malignant transformation of a clone of cells from lymphoid progenitor cells. The majority of cases are of B-cell origin but it can also arise from T-cell precursors. Lymphoid precursors proliferate and replace the normal cells of the bone marrow and blasts spill into the peripheral circulation. It can be distinguished from other malignancies of lymphoid ...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1987
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107688708000218